In Shirley Jackson's "The Third Baby's the Easiest" (1949), which she incorporated into her memoir "Life Among the Savages" (1953), the pregnant narrator receives a shot in the hospital, and wonders about its effect: "[...] I am always afraid with nurses that they feel that the psychological effect of a hypodermic is enough, and that I am actually being inoculated with some useless, although probably harmless, concoction." She may not call it a placebo, but the concept long predates the twentieth century, as does "placebo" itself, which derives from the Vulgate Latin of Psalm 116:9: "Placebo Domino in regione vivorum" ("I will please the Lord in the land of the living"). (Andrew Shields, #111words, 15 January 2023)

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"Some useless, although probably harmless, concoction": The unnamed "placebo effect" in Shirley Jackson's "The Third Baby's the Easiest" (1949)